Microtubule destabilising agents: far more than just antimitotic anticancer drugs

Dementia Care: More Than Just Prescription Drugs.

In this issue of American Family Physician, Dr. Epperly and colleagues review therapies for managing the cognitive and functional symptoms of Alzheimer disease.1 Although the review discusses nonpharmacologic therapies, it focuses primarily on medications that are widely used in practice. Indeed, prescriptions for medications to treat cognitive impairment have increased worldwide as much as six...

Combretastatins: more than just vascular targeting agents?

Several prodrugs of the naturally occurring combretastatins have undergone extensive clinical evaluation as vascular targeting agents (VTAs). Their increased selectivity toward endothelial cells together with their innate ability to rapidly induce vascular shutdown and inhibit tumor growth at doses up to 10-fold less than the maximum tolerated dose led to the clinical evaluation of combretastat...

Angiotensin receptor blockers: more than just blood pressure lowering drugs?

H ypertensive patients have an excess of other cardiovascular risk factors, including hyperlipidaemia. Because various antihypertensive drugs, especially diuretics and beta blockers, adversely affect lipid metabolism, these drugs may increase associated risks for coronary artery disease and thus offset some of the beneficial effects of blood pressure reduction. The renin angiotensin system is a...

More Than Just Another Pretty Face: Embodied Conversational Interface Agents

Introduction Both animals and humans manifest social qualities. Dogs recognize dominance and submission, stand corrected by their superiors, demonstrate consistent personalities, and so forth. On the other hand, only humans communicate using language, and carry on conversations with one another. And the skills of conversation have developed in humans in such a way as to exploit all of the uniqu...

More than just vanilla.